Dengue and Zika are both mosquito-borne viral diseases transmitted primarily by *Aedes* mosquitoes sharing similar transmission dynamics. Dengue virus (DENV) is a major global health threat, causing an estimated 390 milion infections annually, and can lead to severe, sometimes fatal, hemorrhagic fever. In contrast, Zika virus (ZIKV) gained notoriety for its link to severe birth defects, including microcephaly when infection occurs during pregnancy .

While both diseases cause fever, rash, and joint pain, dengue is typically characterized by high fever, severe headache, pain behind the eyes, and muscle/joint pain . Zika symptoms are usually milder. The viruses are closely related, and outbreaks often occur in similar geographic settings, posing significant and overlapping public health challenges .

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